skin brightening, skin lightening, strong antioxidant properties
octadecenedioic acid 1%, 97% tetrahydrocurcuminoids (from Turmeric) >.5%, pycnogenol(pine bark extract), HP-Licorice Complex+
Pigment Regulator Cream contains two powerful pigmentation reducing ingredients that not only have clinical backing but are especially less sensitizing to the skin. This treatment is an exceptional option for those who want an alternative to hydroquinone or just can’t tolerate many of the other actives targeted for pigmentation related concerns.
Due to the tetrahydrocurcuminoids and pycnogenol (also contributes skin whitening benefits) this treatment also delivers significant anti-aging and anti-inflammation benefits.
Otadecenedioic acid is obtained by biofermentation from natural and vegatable oleic acid. It is a skin brightening ingredient with a new mechanism of action that helps inhibit the entire metabolic pathway of melanin synthesis from the nucleus of the melanocyte. By reducing the nucleus of the tyrosinase mRNA, tyrosinase and melanin production is decreased.
In a clinical study of volunteeers ages 18-40 years applied 2 formulations – a cream containing 1% otadecenedioic acid vs 2% Arbutin in the same formulation base. Twice daily random applications where applied for 8 weeks followed by a 4 week regressive period. Specialized equipment was used every two weeks for 3 months to measure lightness, clarity, and melanin quantity parameters. Result – on significant difference between Arbutin and otadecenedioc acid for the three parameters. Melanin decreased by 16.3% in just 2 weeks. After 8-week treatment -22% melanin quantity reduction with otadecenedioic acid.
Tetrahydrocurcuminoids (THC) is a specialized ingredient are derived from curcuminoids (extracted from the roots of curcuma longa, commonly known as turmeric root). Tetrahydrocurcuminoids are phenolic in nature, acting as antioxidants, protecting against free radicals and preventing the generation of free radicals. Unlike yellow curcuminoids, THC is a colorless compound.
Tetrahydrocurcumin has been shown to efficiently inhibit tyrosinase. As such, it is an effective skin lightening agent with multifunctional topical benefits. It has been tested to determine its safety for topical use with no irritant or sensitization side effects.
Hydroquinone, which is extensively used in the treatment of hyperpigmentation disorders is associated with known side effects. Fortunately, safer and natural depigmenting actives are available that have clinically validated positive results. A randomized, placebo controlled study in 50 human subjects, showed that the depigmenting effects of 0.25 percent tetrahydrocurcumin cream and 4 percent hydroquinone cream were comparable in a four week trial with tetrahydrocurcumin showing no adverse effects (unlike hydroquinone).
The anti-inflammatory effects of THC combined with their efficient antioxidant action render them useful as ingredients in skin lightening and brightening products, anti-aging formulations, and topical formulations designed to maintain general skin health and integrity.
Also, additional amount (in addition to amounts already in our bases) a well proven additional amount of our special HP-Licorice Complex has been included – an ingredient both skin brigthening and calming to the skin.
The key ingredients (as in 99% of our treatments) go through our proprietary Actives Micro-Encapsulation Process. This process encapsulates key active ingredients in pharmaceutical grade phospholipids that enhances the absorption of these ingredients while also reducing irritation and delivering essential nutrients for overall skin health.
All cream bases contain additional bio-active complexes. They deliver added soothing, antioxidant, and skin barrier enhancing benefits. See Details About Bases and Complexes for further information.
Clinical studies resulted in beneficial effects after 2 weeks but may take about 12 weeks.
Best used 2 X daily on clean and still slightly moist skin.
Apply under moisturizer.
See How to Use Treatments for further instructions.
octadecenedioic acid .1%, 97% tetrahydrocurcuminoids (from Turmeric) >.5%, pycnogenol (pine bark extract), HP-Licorice Complex+
+ = additional amounts
Choose from one of these bases when placing your order above – Help selecting your base
1 oz treatment pump bottle